Invitrogen™ Human LRFN3 (aa 374-415) Control Fragment Recombinant Protein

Product Code. 30199113

Brand: Invitrogen™ RP100946

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (98%), Rat (98%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-61839 (PA5-61839. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

LRFN3 is one of a family of five transmembrane glycoproteins that are highly expressed in neuronal tissues. LRFN proteins share leucine-rich repeat (LRR)-immunoglobulin-like (Ig)-fibronectin type III (Fn)-transmembrane domain structure with other members of the LRR-Ig-Fn protein superfamily such as the Slitrk family of proteins. Expression of LRFN1, -3, and -4 mRNA was detected in embryonic neuronal cells, while Lrfn2 and Lrfn5 expression was primarily restricted to more mature cells. LRFN1, -2, and -4 bound to PDZ domains of postsynaptic PSD95, re-distributing PSD95 to the cell periphery. It has been suggested that the Lrfn proteins play a role in the developing and/or mature vertebrate nervous system.

Specifications

• Accession Number: Q9BTN0
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Blocking Assay, Control
• Formulation: 1 M urea, PBS with no preservative; pH 7.4
• Gene ID (Entrez): 79414
• Name: Human LRFN3 (aa 374-415) Control Fragment
• Quantity: 100 μL
• Regulatory Status: RUO
• Gene Alias: A530045B06Rik; EMBL:AAI58863.1, ECO:0000312; fibronectin type III, immunoglobulin and leucine rich repeat domains 1; FIGLER1; leucine rich repeat and fibronectin type III domain containing 3; leucine-rich repeat and fibronectin type-III domain-containing protein 3; LRFN3; lrfn3 {ECO:0000312; PubMed:18227064}; RGD:1305567}; Salm4; Synaptic adhesion-like molecule 4; synaptic adhesion-like molecule 4 {ECO:0000303; UNQ5865/PRO34192
• Common Name: LRFN3
• Gene Symbol: LRFN3
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: EATAAVELTVGPPPPPQLANSTSCDPPRDGDPDALTPPSAAS
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining