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Invitrogen™ Human LINGO1 (aa 71-110) Control Fragment Recombinant Protein

Product Code. 30201655
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30201655

Brand: Invitrogen™ RP108012

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This item is not returnable. View return policy

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-111723 (PA5-111723. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors (PubMed:14966521, PubMed:15694321). Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination (PubMed:15895088). Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development. [UniProt]
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q96FE5
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 84894
Name Human LINGO1 (aa 71-110) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias 4930471K13Rik; AV148400; LERN1; leucine rich repeat and Ig domain containing 1; leucine rich repeat neuronal 6 A; leucine-rich repeat; leucine-rich repeat and immunoglobulin domain-containing protein 1; Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1; leucine-rich repeat neuronal 6 A; leucine-rich repeat neuronal protein 1; Leucine-rich repeat neuronal protein 6 A; Lingo1; LINGO-1; LRRN6A; UNQ201; UNQ201/PRO227
Common Name LINGO1
Gene Symbol LINGO1
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence TETRLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAV
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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