Invitrogen™ Human LILRA2 (CD85h, ILT1) Fc Chimera Recombinant Protein

Product Code. 17945581

Brand: Invitrogen™ RP88113

Description

Recombinant Protein

It is recommended that the protein be aliquoted for optimal storage. It is recommended that sterile water (1205 μL) be added to the vial to prepare a stock solution of 0.83 mg/mL. Concentration is measured by UV.

Leukocyte Ig-like receptors (LIRs) are a family of immunoreceptors expressed predominantly on monocytes and B cells and at lower levels on dendritic cells and natural killer (NK) cells. All LIRs in subfamily B have an inhibitory function (LILRB1; MIM 604811). LIRs in subfamily A, with short cytoplasmic domains lacking an immunoreceptor tyrosine-based inhibitory motif (ITIM) and with trans membrane regions containing a charged arginine residue, may initiate stimulatory cascades. One member of subfamily A (LILRA3; MIM 604818) lacks a transmembrane region and is presumed to be a soluble receptor.

Specifications

• Accession Number: Q8N149
• For Use With (Application): Control, Neutralization
• Format: Lyophilized
• Formulation: PBS with 0.01% mannitol, 5-8% trehalose, 0.01% Tween 80 and no preservative; pH 7.4
• Gene ID (Entrez): 11027
• Molecular Weight (g/mol): 92.7 kDa
• Name: Human LILRA2 (CD85h, ILT1) Fc Chimera
• pH Range: 7.4
• Purification Method: Purified
• Quantity: 100 μg
• Storage Requirements: -20°C, Avoid Freeze/Thaw Cycles
• Regulatory Status: RUO
• Endotoxin Concentration: <1.0 EU/μg
• Gene Alias: CD85 antigen-like family member H; CD85h; ILT1; ILT-1; Immunoglobulin-like transcript 1; leucocyte Ig-like receptor A2; leukocyte immunoglobulin like receptor A2; leukocyte immunoglobulin-like receptor 7; Leukocyte immunoglobulin-like receptor subfamily A member 2; leukocyte immunoglobulin-like receptor subfamily A member 2 soluble; leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2; LILRA2; LIR7; LIR-7
• Common Name: LILRA2
• Gene Symbol: LILRA2
• Product Type: Protein
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Protein Tag: Fc-tag
• Sequence: Human LILRA2, amino acids Met1-Asn449 (Accession # NP_001124389.2) with a C-terminal human IgG1 Fc region
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: HEK293 cells
• Form: Lyophilized
• Purity or Quality Grade: >95% as determined by SDS-PAGE.