Human Lgr5/GPR49 Antibody, R&D Systems™

Mouse Monoclonal Antibody has been used in 2 publications

Brand:  R&D Systems MAB8078

Product Code. 18168770

Description

Lgr5/GPR49 Monoclonal specifically detects Lgr5/GPR49 in Human samples. It is validated for Flow Cytometry, Agonist Activity, Immunocytochemistry, CyTOF-ready.

Specifications

• Antigen: Lgr5/GPR49
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene Accession No.: O75473
• Gene Symbols: LGR5
• Immunogen: Chinese hamster ovary cell line CHO-derived recombinant human Lgr5/GPR49 Met1-Ile560 Accession # O75473
• Quantity: 100 μg
• Gene ID (Entrez): 8549
• Reconstitution: Reconstitute at 0.5 mg/mL in sterile PBS.
• Content And Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
• Isotype: IgG2a

• Applications: Flow Cytometry, Agonist Activity, Immunocytochemistry, CyTOF
• Clone: 707042
• Dilution: Flow Cytometry 2.5 ug/10^6 cells, Agonist Activity, Immunocytochemistry 8-25 ug/mL, CyTOF-ready
• Gene Alias: FEX, G protein-coupled receptor 49, GPR49, GPR49G-protein coupled receptor HG38, GPR67, G-protein coupled receptor 49, G-protein coupled receptor 67, GRP49, HG38, leucine-rich repeat containing G protein-coupled receptor 5, leucine-rich repeat-containing G protein-coupled receptor 5, leucine-rich repeat-containing G-protein coupled receptor 5, MGC117008, orphan G protein-coupled receptor HG38
• Host Species: Mouse
• Purification Method: Protein A or G purified from hybridoma culture supernatant
• Primary or Secondary: Primary
• Test Specificity: Detects human Lgr5/GPR49 in ELISA. Stains human and mouse Lgr5 transfected cells but not irrelevant transfectants in Flow Cytometry and Immunocytochemistry. This antibody, also known as “RD42”, has been found to detect an epitope in C-terminal LRR cap of LGR5 (Ref. 1).
• Target Species: Human
• Form: Purified