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Invitrogen™ Human LAMP2 Synthetic Peptide

Product Code. 15206529
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Quantity:
50 μg
Unit Size:
50µg
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15206529 50 μg 50µg
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Product Code. 15206529 Supplier Invitrogen™ Supplier No. PEP0312

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Description

Synthetic Peptide

LAMP-2 Synthetic Peptide, PEP-0312, from Invitrogen.

LAMP2 (Lysosome-associated membrane glycoprotein 2, CD107b) is a member of a family of membrane glycoproteins. LAMP2 provides selectins with carbohydrate ligands, and may play a role in tumor cell metastasis, and have a function in the protection, maintenance, and adhesion of the lysosome. Prior to posttranslational modification, LAMP2 is approximately 46 kDa polypeptide. Mature, functional LAMP2 is extensively glycosylated with a variety of different N-linked and O-linked oligosaccharides with a total molecular weight of about 100-130 kDa. LAMP 2 has a structure comprised of a large amino-terminal intra-lysosomal domain, a hydrophobic trans-membrane domain, and a short carboxyl-terminal cytoplasmic tail. LAMP2 is used to monitor a very selective form of autophagy called chaperone-mediated autophagy. LAMP 2 has a structure comprised of a large amino-terminal intra-lysosomal domain, a hydrophobic trans-membrane domain, and a short carboxyl-terminal cytoplasmic tail. The LAMP protein has 3 variant forms: LAMP-2A, -2B, and 2C. LAMP2, together with CD107a/LAMP-1, is a major constituent of lysosomal membrane. The LAMP proteins are involved in lysosome biogenesis and are required for fusion of lysosomes with phagosomes, and LAMP2 is an important regulator in successful phagosomal maturation. LAMP2 deficiency causes an accumulation of autophagosomes in many tissues leading to cardiomyopathy and myopathy (Danon’s disease).
TRUSTED_SUSTAINABILITY

Specifications

Gene ID (Entrez) 3920
Species Human
Purification Method purified
Accession Number P13473
Common Name Human LAMP2
Concentration 200 μg/mL
Content And Storage -20°C
Description Synthetic Peptide
Format Liquid
Formulation PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
For Use With (Application) Blocking Assay, Control
Gene Symbol LAMP2
Lyophilized No
Preservative 0.02% sodium azide
Product Type Peptide
Quantity 50 μg
Regulatory Status RUO - research use only
Storage Buffer PBS
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