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Invitrogen™ Human Lamin B Receptor Control Fragment Recombinant Protein

Product Code. 30212054
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30212054

Brand: Invitrogen™ RP105228

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This item is not returnable. View return policy

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (62%), Rat (62%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-66473 (PA5-66473. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q14739
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 3930
Name Human Lamin B Receptor Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias 3-beta-hydroxysterol Delta (14)-reductase; AI505894; C-14 sterol reductase; C14SR; Delta(14)-sterol reductase LBR; delta(14)-sterol reductase LBR; lamin-B receptor; Delta-14-SR; DHCR14B; FLJ43126; ic; ichthyosis; integral nuclear envelope inner membrane protein; lamin B receptor; lamin-B receptor; lamin-b receptor-like protein; Lbr; LMN2R; MGC9041; NBP60; PHA; PRO0650; sb:cb406; Sterol C14-reductase; TDRD18; tudor domain containing 18; wu:fb75h08; wu:fc47b04; wu:fd36b07; zgc:86649
Common Name Lamin B Receptor
Gene Symbol LBR
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence EARREVEVKLTPLILKPFGNSISRYNGEPEHIERNDAPHKNTQEKFNLSQESSYIATQYSLRPRREEVKLKEIDSKEEKYVAKELAVRTF
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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