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Invitrogen™ Human KCNN4 (aa 319-425) Control Fragment Recombinant Protein

Product Code. 30199965
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30199965

Brand: Invitrogen™ RP110219

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This item is not returnable. View return policy

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (85%), Rat (85%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-144709 (PA5-144709. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

The protein encoded by this gene is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization, which promotes calcium influx. The encoded protein may be part of the predominant calcium-activated potassium channel in T-lymphocytes. This gene is similar to other KCNN family potassium channel genes, but it differs enough to possibly be considered as part of a new subfamily.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number O15554
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 3783
Name Human KCNN4 (aa 319-425) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias DHS2; HIK1; hIKCa1; hKCa4; hSK4; IK; IK1; IKCa; IKCA1; intermediate conductance calcium-activated potassium channel protein 1; intermediate conductance calcium-activated potassium channel protein 4; intermediate conductance K channel; intermediate-conductance Ca-activated K channel; intermediate-conductance calcium-activated potassium channel; KCa3.1; KCA4; KCNN 4; KCNN4; mIKCa1; potassium calcium-activated channel subfamily N member 4; potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4; potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4; putative erythrocyte intermediate conductance calcium-activated potassium Gardos channel; putative Gardos channel; rKCNN4c; rSK4; SK4; SKCa 4; SKCa4; SKCas; small conductance calcium-activated potassium channel 4
Common Name KCNN4
Gene Symbol Kcnn4
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence LQEAWMFYKHTRRKESHAARRHQRKLLAAINAFRQVRLKHRKLREQVNSMVDISKMHMILYDLQQNLSSSHRALEKQIDTLAGKLDALTELLSTALGPRQLPEPSQQ
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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