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Invitrogen™ Human KCNH3 (aa 712-792) Control Fragment Recombinant Protein

Product Code. 30207985
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30207985

Brand: Invitrogen™ RP100965

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This item is not returnable. View return policy

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (96%), Rat (96%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-62314 (PA5-62314. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

The protein encoded by this gene is a voltage-gated potassium channel alpha subunit predominantly expressed in the forebrain. Studies in mice have found that cognitive function increases when this gene is knocked out. In humans, the encoded protein has been shown to be capable of binding glycoprotein 120 of the human immunodeficiency virus type 1 (HIV-1) envelope. Two transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q9ULD8
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 23416
Name Human KCNH3 (aa 712-792) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias AU019351; Bec1; Brain-specific eag-like channel 1; C030044P22Rik; ELK channel 2; Elk2; ether a go-go like; ether-a-go-go K(+) channel family member; ether-a-go-go-like potassium channel 2; KCNH3; KIAA1282; Kv12.2; Melk2; potassium channel, voltage gated eag related subfamily H, member 3; potassium voltage-gated channel subfamily H member 3; potassium voltage-gated channel, subfamily H (eag-related), member 3; rElk2; voltage-gated potassium channel subunit Kv12.2
Common Name KCNH3
Gene Symbol KCNH3
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence EVDTSSLSGDNTLMSTLEEKETDGEQGPTVSPAPADEPSSPLLSPGCTSSSSAAKLLSPRRTAPRPRLGGRGRPGRAGALK
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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