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Invitrogen™ Human JTB (aa 36-105) Control Fragment Recombinant Protein

Product Code. 30212815
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30212815

Brand: Invitrogen™ RP89171

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This item is not returnable. View return policy

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (84%), Rat (84%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-52307 (PA5-52307. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Required for normal cytokinesis during mitosis. Plays a role in the regulation of cell proliferation. May be a component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Increases AURKB activity. Inhibits apoptosis induced by TGFB1. Overexpression induces swelling of mitochondria and reduces mitochondrial membrane potential.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number O76095
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 10899
Name Human JTB (aa 36-105) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias hJT; HJTB; HSPC222; Jtb; jumping translocation breakpoint; jumping translocation breakpoint protein; PAR; PAR protein; Prostate androgen-regulated protein; protein JTB
Common Name JTB
Gene Symbol JTB
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence EEKLSASTSNLPCWLVEEFVVAEECSPCSNFRAKTTPECGPTGYVEKITCSSSKRNEFKSCRSALMEQRL
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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