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Invitrogen™ IL-29 Human ELISA Kit

For the quantitative detection of human IL-29.

Brand:  Invitrogen™ BMS2049

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15561567

  • £377.00 / 96 tests


EU Stock 2
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Includes: Aluminium pouch(es) with a Microwell Plate coated with monoclonal antibody to human IL-29
Biotin-Conjugate anti-human IL-29 monoclonal antibody
Streptavidin-HRP
Human IL-29 Standard lyophilized, 2ng/mL upon reconstitution
Sample Diluent
Assay Buffer Concentrate 20x (PBS with 1% Tween 20 and 10% BSA)
Wash Buffer Concentrate 20x (PBS with 1% Tween 20)
Substrate Solution (tetramethyl-benzidine)
Stop Solution (1M Phosphoric acid)
Blue-Dye
Green-Dye
Red-Dye
Adhesive Films

Description

Description

IFN-lambdas constitute a novel family of interferons that mediate the induction of anti-viral protection in a wide variety of cells. There are three members in this family, namely lambda1, lambda2, and lambda3, which are also known as IL-29, IL-28A, and IL-28B, respectively. Similar to type I IFNs, IFN-lambdas activate an intracellular signaling to promote gene expression. IFN-lambdas mediate their anti-viral protection through a class II cytokine receptor complex composed of two essential receptor proteins, CRF2-12/IFN-lambdaR1, which is unique to IFN-lambdas, and CFR2-4/IL-10R2, which is shared with IL-10, IL-22, and IL-26 receptors. The IFN-lambdas, IL-28 and IL-29, have recently been reported to prime dendritic cells to induce proliferation of Foxp3-bearing regulatory T cells. DCs that differentiate in response to IFN-lambdas express high levels of class I and II MHC gene products, but low levels of costimulatory molecules. Moreover, these cells can specifically induce IL-2-dependent proliferation of CD4+CD25+FOXP3+ T cells with contact-dependent suppressive activity.
Specifications

Specifications

Q8IU54
Biotin
282618
Pre-coated 96 well plate, Standard, Sample Diluent, Assay Buffer concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
RUO
50 μL
2°C to 8°C
3 hr. 30 min.
IL-29,IL29
7.1%
HRP
Human
15.6-1,000 pg/mL
ELISA
Colorimetric Microplate Reader
ELISA Kit
2.0 pg/mL
Plasma, 50 μL|Serum, 50 μL|Supernatant, 50 μL
1 hr. 20 min.
Human
IFNL1, Interleukin 29
7.6%
96 Tests
Supernatant
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For Research Use Only