Gibco™ Human IL-24 Recombinant Protein, PeproTech®

Product Code. 17860343

Brand: Gibco™ 20035250UG

Description

Recombinant Protein

200-35-1MG will be provided as 2 x 500 μg (200-35-500UG). Recombinant Human IL-24 is an 18.9 kDa glycoprotein that contains 161 amino acid residues, including a C-terminal His-tag. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

Interleukin 24 (IL-24)/melanoma differentiation-associated gene-7 (mda-7) encodes a secreted protein that exhibits significant homology to the interleukin 10 (IL-10) family of cytokines. The human IL-24 is secreted by activated peripheral blood mononuclear cells and binds two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2 resulting in the activation of JAK/STAT signaling pathways. Mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner.

Specifications

• Accession Number: Q13007
• For Use With (Application): Functional Assay
• Formulation: protein with no preservative
• Gene ID (Entrez): 11009
• Molecular Weight (g/mol): 18.9 kDa
• Name: Human IL-24
• Quantity: 250 μg
• Source: CHO cells
• Regulatory Status: RUO
• Endotoxin Concentration: <1 EU/ μg
• Gene Alias: C49A; Cytokine-like protein Mob-5; FISP; IL 24; IL10B; Il24; IL-24; IL-4-induced secreted protein; Interleukin; interleukin 24; interleukin-24; Mda7; MDA-7; melanocyte-associated Mda-7; melanoma differentiation-associated gene 7 protein; Mob5; ST16; suppression of tumorigenicity 16 (melanoma differentiation); Suppression of tumorigenicity 16 protein; Th2-specific cytokine FISP
• Common Name: IL24
• Gene Symbol: IL24
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Protein Tag: His-tag
• Sequence: QEFHFGPCQV KGVVPQKLWE AFWAVKDTMQ AQDNITSARL LQQEVLQNVS DAESCYLVHT LLEFYLKTVF KNYHNRTVEV RTLKSFSTLA NNFVLIVSQL QPSQENEMFS IRDSAHRRFL LFRRAFKQLD VEAALTKALG EVDILLTWMQ KFYKLHHHHH H
• Content And Storage: -20°C
• Expression System: CHO cells
• Form: Lyophilized
• Purity or Quality Grade: ≥ 95% by SDS-PAGE gel and HPLC analyses.