Invitrogen™ eBioscience™ Human IL-2, Recombinant Protein, Carrier-Free

Product Code. 15558736

Brand: Invitrogen™ 34802985

Description

Human Recombinant Protein

Human IL-2 (also known as TCGF) is a ∽15 kDa factor produced mainly by activated CD4⁺ T cells. IL-2 induces cell cycle progression of resting cells in an antigen non-specific manner and allows clonal expansion of activated T cells. IL-2 also acts on activated B cells, monocytes, NK, LAK cells, and on oligodendroglial cells in vitro. In addition, IL-2 plays a role in hematopoiesis, tumor surveillance and anti-inflammatory reactions and hence is a central regulator of the immune response. Non-glycosylated IL-2 is biologically active.

Specifications

• Concentration: 0.5mg/mL
• For Use With (Application): Cytokine Bioassay, ELISA
• Formulation: Sterile liquid: 40mM acetate, 0.2M NaCl, pH 5. 0.22μm filtered.
• Molecular Weight (g/mol): 15kDa
• Name: IL-2
• Purification Method: SDS-PAGE
• Quantity: 500 μg
• Source: E. coli
• Storage Requirements: Store at less than or equal to -70°C.
• Regulatory Status: RUO
• Structural Form: E. coli
• Endotoxin Concentration: Less than 0.01ng/μg cytokine as determined by the LAL assay.
• Gene Symbol: Interleukin-2
• Biological Activity: The ED50 of this protein, as measured by CTLL-2 proliferation assay, is less than or equal to 175pg/mL. This corresponds to a specific activity of greater than or equal to 5.7 x 10⁶ Units/mg.
• Product Type: Recombinant Protein, Carrier-Free
• Conjugate: Unconjugated
• Cross Reactivity: Human
• Recombinant: Recombinant
• Purity or Quality Grade: >98%