Invitrogen™ Human ICEBERG (aa 48-90) Control Fragment Recombinant Protein

Product Code. 30211515

Brand: Invitrogen™ RP97330

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (47%), Rat (47%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-58451 (PA5-58451. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Inhibits generation of IL-1-beta by interacting with caspase-1 and preventing its association with RIP2. Down-regulates the release of IL1B.

Specifications

• Accession Number: P57730
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Blocking Assay, Control
• Formulation: 1 M urea, PBS with no preservative; pH 7.4
• Gene ID (Entrez): 59082
• Name: Human ICEBERG (aa 48-90) Control Fragment
• Quantity: 100 μL
• Regulatory Status: RUO
• Gene Alias: CARD18; caspase recruitment domain family member 18; caspase recruitment domain family, member 18; caspase recruitment domain-containing protein 18; Caspase-1 inhibitor Iceberg; ICEBERG; ICEBERG caspase-1 inhibitor; pseudo-ICE; UNQ5804; UNQ5804/PRO19611
• Common Name: ICEBERG
• Gene Symbol: CARD18
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: DTVMDKARVLIDLVTGKGPKSCCKFIKHLCEEDPQLASKMGLH
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining