Invitrogen™ Human HP1 beta (aa 166-185) Control Fragment Recombinant Protein

Product Code. 30202305

Brand: Invitrogen™ RP110054

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-145003 (PA5-145003. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Specifications

• Accession Number: P83916
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Blocking Assay, Control
• Formulation: 1 M urea, PBS with no preservative; pH 7.4
• Gene ID (Entrez): 10951
• Name: Human HP1 beta (aa 166-185) Control Fragment
• Quantity: 100 μL
• Regulatory Status: RUO
• Gene Alias: CBX; Cb x 1; Cbx-rs2; chromobox 1; chromobox homolog 1; chromobox homolog 1 (HP1 beta homolog Drosophila); chromobox protein homolog 1; E430007M08Rik; heterochromatin protein 1 homolog beta; heterochromatin protein 1-beta; heterochromatin protein p25; heterochromatin protein p25 beta; HGNC:1551; HP1 beta; HP1 beta homolog; HP1B; Hp1beta; HP1-BETA; HP1Hsbeta; HP1Hs-beta; M31; MOD1; modifier 1 protein; p25beta
• Common Name: HP1 beta
• Gene Symbol: CBX1
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: ERLTWHSYPSEDDDKKDDKN
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining