Invitrogen™ Human HNF6 (aa 160-297) Control Fragment Recombinant Protein

Product Code. 30196942

Brand: Invitrogen™ RP100744

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (99%), Rat (99%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-51938 (PA5-51938. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Hepatocyte nuclear factor 6 is a CUT homeobox family protein which is a transcription factor and contains a CUT DNA-binding domain and a homeobox DNA-binding domain. It is an upstream regulator of several genes involved in the pathogenesis of maturity-onset diabetes of the young. HNF6 is a ligand of the FOXM1 transcription factor network. HNF6, along with HNF4, controls gene expression in the liver. The expression levels of HNF6 and HNF4 rise steadily during development and that up- or down regulation of HNF6 and HNF4 expression generate premature or delayed expression of the g6pc gene.

Specifications

• Accession Number: Q9UBC0
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Blocking Assay, Control
• Formulation: 1 M urea, PBS with no preservative; pH 7.4
• Gene ID (Entrez): 3175
• Name: Human HNF6 (aa 160-297) Control Fragment
• Quantity: 100 μL
• Regulatory Status: RUO
• Gene Alias: D9Ertd423e; hepatic nuclear factor 6; hepatocyte nuclear factor 6; hepatocyte nuclear factor 6 alpha; hepatocyte nuclear factor 6, alpha; Hfh12; HNF-3/forkhead homolog 12; hnf6; HNF-6; Hnf6a; HNF-6 A; Hnf6b; Oc1; OC-1; One cut domain family member 1; one cut domain, family member 1; one cut domain, family member 1, like; one cut homeobox 1; Onecut1; onecut-1 isoform a; onecut-1 isoform b; onecut1 protein; onecut1l; transcription factor; hepatocyte nuclear factor 6; hnf-6; zgc:65904; zgc:77450
• Common Name: HNF6
• Gene Symbol: ONECUT1
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: SMNNLYTPYHKDVAGMGQSLSPLSSSGLGSIHNSQQGLPHYAHPGAAMPTDKMLTPNGFEAHHPAMLGRHGEQHLTPTSAGMVPINGLPPHHPHAHLNAQGHGQLLGTAREPNPSVTGAQVSNGSNSGQMEEINTKEV
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining