Invitrogen™ Human HMGA1 (aa 61-94) Control Fragment Recombinant Protein

Product Code. 30206220

Brand: Invitrogen™ RP109158

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (94%), Rat (94%). This recombinant protein control fragment may be used for blocking experiments. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

HMGA1 encodes a non-histone protein involved in many cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of A+T-rich regions in double-stranded DNA. It has little secondary structure in solution but assumes distinct conformations when bound to substrates such as DNA or other proteins. The encoded protein is frequently acetylated and is found in the nucleus.

Specifications

• Accession Number: P17096
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Blocking Assay, Control
• Formulation: 1 M urea, PBS with no preservative; pH 7.4
• Gene ID (Entrez): 3159
• Name: Human HMGA1 (aa 61-94) Control Fragment
• Quantity: 100 μL
• Regulatory Status: RUO
• Gene Alias: AL023995; HGNC:5010; high mobility group AT-hook 1; high mobility group AT-hook protein 1; high mobility group HMGA1A; high mobility group HMGA1B; high mobility group protein; high mobility group protein 1 A; high mobility group protein A1; high mobility group protein A1A; high mobility group protein A1B; high mobility group protein HMG-I/HMG-Y; high mobility group protein I; high mobility group protein R; high mobiliy group protein A1B; high-mobility group (nonhistone chromosomal) protein isoforms I and Y; HMGA1; Hmga1a; Hmga1b; Hmgi; HMG-I(Y); HMGIY; HMG-R; Hmgy; MGC12816; MGC4242; MGC4854; nonhistone chromosomal high-mobility group protein HMG-I/HMG-Y; non-histone protein; non-histone protein; HMGA1A; non-histone protein; HMGA1B; OTTHUMP00000016222; OTTHUMP00000016223; OTTHUMP00000016224; OTTHUMP00000039618
• Common Name: HMGA1
• Gene Symbol: HMGA1
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: PKGSKNKGAAKTRKTTTTPGRKPRGRPKKLEKEE
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining