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Invitrogen™ Human HJURP (aa 349-494) Control Fragment Recombinant Protein

Product Code. 30195064
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30195064

Brand: Invitrogen™ RP104578

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This item is not returnable. View return policy

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (45%), Rat (45%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-82963 (PA5-82963. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Holliday junction recognition protein (HJURP) is a centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres. It acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. HJURP prevents CENPA-H4 tetramerization and prevents premature DNA binding by the CENPA-H4 tetramer. It directly binds to Holliday junctions.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q8NCD3
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 55355
Name Human HJURP (aa 349-494) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias 14-3-3-associated AKT substrate; 6430706D22Rik; A730008H23Rik; C330011F01Rik; FAKTS; fetal liver expressing gene 1; fetal liver expressing gene 1 protein homolog; Fetal liver-expressing gene 1 protein; FLEG1; Gm975; hFLEG1; Hjurp; Holliday junction recognition protein; mFleg1; RGD1305846; Up-regulated in lung cancer 9; URLC9
Common Name HJURP
Gene Symbol HJURP
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence RKTGLKLEKAFLEVNRPQIHKLDPSWKERKVTPSKYSSLIYFDSSATYNLDEENRFRTLKWLISPVKIVSRPTIRQGHGENRQREIEIRFDQLHREYCLSPRNQPRRMCLPDSWAMNMYRGGPASPGGLQGLETRRLSLPSSKAKA
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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