Invitrogen™ Human HES5 (aa 3-30) Control Fragment Recombinant Protein

Product Code. 30207423

Brand: Invitrogen™ RP107431

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (96%), Rat (96%). This recombinant protein control fragment may be used for blocking experiments. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Hairy and Enhancer-of-split homologues 5 (HES5) is a helix-loop-helix transcriptional factor that negatively regulates cell differentiation during embryogenesis. It contains one basic helix-loop-helix (bHLH) domain and one Orange domain. HES5 is reported to be a down stream effector of the Notch Signaling Pathway and is expressed in advanced ovarian serous adenocarcinomas as well as in cervical squamous carcinoma. Reports also suggest that HES5 is abundantly expressed in osteoarthritis along with Notch1 and Jagged1.

Specifications

• Accession Number: Q5TA89
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Blocking Assay, Control
• Formulation: 1 M urea, PBS with no preservative; pH 7.4
• Gene ID (Entrez): 388585
• Name: Human HES5 (aa 3-30) Control Fragment
• Quantity: 100 μL
• Regulatory Status: RUO
• Gene Alias: BHLHB38; Class B basic helix-loop-helix protein 38; hairy and enhancer of split 5; hairy and enhancer of split 5 (Drosophila); hes family bHLH transcription factor 5; Hes5; Hes-5; RP3-395M20.5; Transcription factor HES-5
• Common Name: HES5
• Gene Symbol: HES5
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: PSTVAVELLSPKEKNRLRKPVVEKMRRD
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining