Invitrogen™ Human HARS2 (aa 30-54) Control Fragment Recombinant Protein

Product Code. 30198590

Brand: Invitrogen™ RP96865

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (73%), Rat (73%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-57474 (PA5-57474. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is an enzyme belonging to the class II family of aminoacyl-tRNA synthetases. Functioning in the synthesis of histidyl-transfer RNA, the enzyme plays an accessory role in the regulation of protein biosynthesis. The gene is located in a head-to-head orientation with HARS on chromosome five, where the homologous genes likely share a bidirectional promoter. Mutations in this gene are associated with the pathogenesis of Perrault syndrome, which involves ovarian dysgenesis and sensorineural hearing loss. Alternative splicing results in multiple transcript variants of this gene.

Specifications

• Accession Number: P49590
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Blocking Assay, Control
• Formulation: 1 M urea, PBS with no preservative; pH 7.4
• Gene ID (Entrez): 23438
• Name: Human HARS2 (aa 30-54) Control Fragment
• Quantity: 100 μL
• Regulatory Status: RUO
• Gene Alias: 4631412B19Rik; D-tyrosyl-tRNA deacylase 1 homolog; EC 6.1.1.21; EGK_16929; HARS2; Hars2l; HARSL; HARSR; HARS-related; HisRS; histidine translase; histidine tRNA ligase 2, mitochondrial (putative); histidine-tRNA ligase homolog; Histidine--tRNA ligase-like; Histidyl-tRNA synthetase; histidyl-tRNA synthetase 2; histidyl-tRNA synthetase 2, mitochondrial; histidyl-tRNA synthetase 2, mitochondrial (putative); histidyl-tRNA synthetase 2, mitochondrial, hisRS; histidyl-tRNA synthetase-like; HO3; PRLTS2; Probable histidine--tRNA ligase, mitochondrial; probable histidyl-tRNA synthetase, mitochondrial; probable histidyl-tRNA synthetase, mitochondrial-like; putative histidyl-tRNA synthetase, mitochondrial; RGD1308426; zinc finger, matrin type 2; Zmat2
• Common Name: HARS2
• Gene Symbol: HARS2
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: AVRCQSQVAEAVLTSQLKAHQEKPN
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining