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Invitrogen™ Human HARS (aa 1-64) Control Fragment Recombinant Protein

Product Code. 30205940
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30205940

Brand: Invitrogen™ RP96931

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This item is not returnable. View return policy

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (86%), Rat (86%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-57708 (PA5-57708. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a cytoplasmic enzyme which belongs to the class II family of aminoacyl-tRNA synthetases. The enzyme is responsible for the synthesis of histidyl-transfer RNA, which is essential for the incorporation of histidine into proteins. The gene is located in a head-to-head orientation with HARSL on chromosome five, where the homologous genes share a bidirectional promoter. The gene product is a frequent target of autoantibodies in the human autoimmune disease polymyositis/dermatomyositis.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P12081
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 3035
Name Human HARS (aa 1-64) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias CMT2W; dead end homolog 1; Dnd1; FLJ20491; HARS; HARS1; HARSL; HARSL protein; HisRS; histidine translase; histidine tRNA ligase; histidine--tRNA ligase; histidine--tRNA ligase, cytoplasmic; Histidyl-tRNA synthetase; histidyl-tRNA synthetase 1; histidyl-tRNA synthetase, cytoplasmic; HRS; im:7136719; MMHRS; Unknown (protein for IMAGE:7951312); USH3B; zgc:92215
Common Name HARS
Gene Symbol HARS1
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence MAERAALEELVKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPKGTRD
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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