Invitrogen™ Human GSK3 alpha (aa 401-483) Control Fragment Recombinant Protein

Product Code. 30199675

Brand: Invitrogen™ RP95197

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (75%), Rat (75%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-83011 (PA5-83011. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Glycogen synthase kinase 3 alpha (GSK3A) is a multifunctional protein serine/threonine kinase implicated in the control of several regulatory proteins and transcription factors. (GSK3A Alias: DKFZp686D0638). Human GSTs can be divided into five main classes: alpha, mu, pi, theta, and zeta. The theta class includes GSTT1 and GSTT2. The GSTT1 and GSTT2 share 55% amino acid sequence identity and both of them were claimed to have an important role in human carcinogenesis. The GSTT1 gene is located approximately 50kb away from the GSTT2 gene. The GSTT1 and GSTT2 genes have a similar structure, being composed of five exons with identical exon/intron boundaries.

Specifications

• Accession Number: P49840
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Blocking Assay, Control
• Formulation: 1 M urea, PBS with no preservative; pH 7.4
• Gene ID (Entrez): 2931
• Name: Human GSK3 alpha (aa 401-483) Control Fragment
• Quantity: 100 μL
• Regulatory Status: RUO
• Gene Alias: 2700086H06Rik; DKFZp686D0638; FA; factor A; glycogen synthase kinase 3 alpha; glycogen synthase kinase 3 alpha b; glycogen synthase kinase 3 alpha b; glycogen synthase kinase-3 alpha; glycogen synthase kinase-3 alpha; GSK3; GSK-3 alpha; GSK-3 [a]; GSK-3 [b]; gsk3a; gsk3ab; gsk-3-alpha; OTTHUMP00000198368; Serine/threonine-protein kinase GSK3A
• Common Name: GSK3 alpha
• Gene Symbol: Gsk3a
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: SFFDELRCLGTQLPNNRPLPPLFNFSAGELSIQPSLNAILIPPHLRSPAGTTTLTPSSQALTETPTSSDWQSTDATPTLTNSS
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining