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Invitrogen™ Human GRASP1 (aa 679-793) Control Fragment Recombinant Protein

Product Code. 30197871
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30197871

Brand: Invitrogen™ RP91910

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This item is not returnable. View return policy

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (99%), Rat (99%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-81882 (PA5-81882. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

PDZ domain-containing proteins, such as PSD-95 and GRIP are thought to play key roles in glutamate receptor plasticity. GRIP-associated proteins (GRASPs) that bind to distinct PDZ domains within GRIP also play key roles in regulation of glutamate receptor function. GRASP-1 is a neuronal rasGEF associated with GRIP and AMPA receptors in vivo (Scannevin and Huganir, 2000). Recent work suggests that GRASP-1 may regulate neuronal ras signaling and contribute to the regulation of AMPA receptor distribution by NMDA receptor activity (Ye et al., 2000).
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q4V328
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 56850
Name Human GRASP1 (aa 679-793) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias 30 kDa C-terminus form; AI854681; DXIm x 47 e; Grasp1; GRASP-1; GRASP-1 C-terminal chain; GRIP1; GRIP-1; GRIP1 associated protein 1; GRIP1-associated protein 1; Gripap1; GRIP-associated protein 1; HCMV-interacting protein; Kiaa1167; mKIAA1167; MPMGp800B12492Q3; Sfc10
Common Name GRASP1
Gene Symbol GRIPAP1
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence KESSAVPARSLSSSPQAQPPRPAELSDEEVAELFQRLAETQQEKWMLEEKVKHLEVSSASMAEDLCRKSAIIETYVMDSRIDVSVAAGHTDRSGLGSVLRDLVKPGDENLREMNK
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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