Invitrogen™ Human GPD1 (aa 323-346) Control Fragment Recombinant Protein

Product Code. 30204920

Brand: Invitrogen™ RP110075

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (92%), Rat (92%). This recombinant protein control fragment may be used for blocking experiments. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

This gene encodes a member of the NAD-dependent glycerol-3-phosphate dehydrogenase family. The encoded protein plays a critical role in carbohydrate and lipid metabolism by catalyzing the reversible conversion of dihydroxyacetone phosphate (DHAP) and reduced nicotine adenine dinucleotide (NADH) to glycerol-3-phosphate (G3P) and NAD+. The encoded cytosolic protein and mitochondrial glycerol-3-phosphate dehydrogenase also form a glycerol phosphate shuttle that facilitates the transfer of reducing equivalents from the cytosol to mitochondria. Mutations in this gene are a cause of transient infantile hypertriglyceridemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Specifications

• Accession Number: P21695
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Blocking Assay, Control
• Formulation: 1 M urea, PBS with no preservative; pH 7.4
• Gene ID (Entrez): 2819
• Name: Human GPD1 (aa 323-346) Control Fragment
• Quantity: 100 μL
• Regulatory Status: RUO
• Gene Alias: AI747587; Gdc1; Gdc-1; glycerol 3-phosphate dehydrogenase; glycerol phosphate dehydrogenase 1, cytoplasmic adult; Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic; glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic; glycerol-3-phosphate dehydrogenase 1; glycerol-3-phosphate dehydrogenase 1 (soluble); glycerolphosphate dehydrogenase 1, cytoplasmic adult; glycerophosphate dehydrogenase; Gpd1; Gpd3; GPD-C; GPDH; GPDH-C; HTGTI; Kiaa4010; mKIAA4010
• Common Name: GPD1
• Gene Symbol: Gpd1
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: MAVYKVCYEGQPVGEFIHCLQNHP
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining