eBioscience™ Human IL-34, Recombinant Protein, Carrier-Free

Human Recombinant Protein

Brand: eBioscience™

Manufacturer Part Number: 34-8684-63

10UG Human IL-34 Recombinant Protein Carrier-Free

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg

Product Code. 15538816

Quantity Price
1 £ 204.0 / 10µg
Estimated Shipment date
from Supplier 09-12-2016
Add to basket

Description and Specification


Conjugate Unlabeled
Cross Reactivity Human
For Use With (Application) Functional Assays
Formulation Lyophilized from 20mM citric acid, pH 3.0
Molecular Weight 52.5kDa
Name IL-34
Purification Method SDS-PAGE and HPLC
Purity >95%
Quantity 10μg
Recombinant Yes
Source HEK 293 cells
Storage Requirements Store lyophilized protein at less than or equal to -20°C. Reconstituted protein solution can be stored with carrier protein (e.g., 0.1% BSA) at less than or equal to -20°C.
Regulatory Status RUO
Structural Form HEK 293 cells (amino acids Asn21-Pro242; Accession # NP_001166243); contains a C-terminal 8X His tag
Endotoxin Concentration Less than 0.1ng/μg cytokine as determined by the LAL assay
Biological Activity The activity of this protein was determined by measuring MCP-1 secretion from normal human peripheral blood cells.
Product Type Recombinant Protein, Carrier-Free

IL-34 is secreted as a dimeric protein and currently belongs to no known cytokine family. It signals via the M-CSF Receptor, also known as CSF-1R and CD115, which is shared with M-CSF. IL-34 has no amino acid sequence homology to M-CSF, but they exhibit similarities in secondary structure and share overlapping functions. IL-34 has been shown to promote myeloid survival, proliferation, and differentiation, and to play a role in osteoclast formation. IL-34 expression has been detected in various tissues and is most abundant in the spleen.