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Gibco™ Human GDF-5 Recombinant Protein, PeproTech®

E. coli Recombinant Protein

Brand:  Gibco™ 120-01-1MG

Additional Details : Weight : 0.16500kg

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Product Code. 17831733

  • £1200.00 / 1mg
Estimated Shipment: 15-08-2024
to see stock.

Description

Description

GDF-5 is expressed in long bones during embryonic development and postnatally in articular cartilage. Mutations in the GDF-5 gene have been implicated in Hunter-Thompson type dwarfism and in Grebe Syndrome, which is characterized by short stature, extra digits, and short and deformed extremities. The mature and functional form of GDF-5 is a homodimer of two 120 amino-acid polypeptide chain (monomers) linked by a single disulfide bond. Each GDF-5 monomer is expressed as the C-terminal part of a precursor polypeptide, which also contains a 27 amino acid signal peptide and a 354 amino acid propeptide. This precursor undergoes intracellular dimerization, and upon secretion it is processed by a furin-type protease.
Specifications

Specifications

P43026
protein with no preservative
27
1 mg
-20°C
<1 EU/μg
GDF5
Unconjugated
APLATRQGKR PSKNLKARCS RKALHVNFKD MGWDDWIIAP LEYEAFHCEG LCEFPLRSHL EPTNHAVIQT LMNSMDPEST PPTCCVPTRL SPISILFIDS ANNVVYKQYE DMVVESCGCR
≥ 98% by SDS-PAGE gel and HPLC analyses.
Functional Assay
8200
Human GDF-5
E. coli
RUO
BDA1C; Bmp14; BMP-14; Bone morphogenetic protein 14; bp; brachypodism; brp; Cartilage-derived morphogenetic protein 1; cartilage-derived morphogenetic protein-1; CDMP1; Cdmp-1; GDF5; GDF-5; growth differentiation factor 5; growth/differentiation factor 5; H-GDF-5; LAP4; LAP-4; Lipopolysaccharide-associated protein 4; LPS-associated protein 4; OS5; radotermin; SYM1B; SYNS2
Human
Recombinant
Lyophilized
Produktvorschläge

Produktvorschläge

Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Zertifikate
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Sonderangebote