Gibco™ Human GDF-2 Recombinant Protein, PeproTech®

Product Code. 17871163

Brand: Gibco™ 12007100UG

Description

Recombinant Protein

Recombinant Human GDF-2 is a 24.1 kDa disulfide-linked homodimeric protein consisting of two 110 amino acid polypeptide chains. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in rodents suggest that this protein plays a role in the adult liver and in differentiation of cholinergic central nervous system neurons.

Specifications

• Accession Number: Q9UK05
• For Use With (Application): Functional Assay
• Formulation: protein with no preservative
• Gene ID (Entrez): 2658
• Molecular Weight (g/mol): 24.1 kDa
• Name: Human GDF-2
• Quantity: 100 μg
• Source: CHO cells
• Regulatory Status: RUO
• Endotoxin Concentration: <1 EU/ μg
• Gene Alias: BMP; BMP9; BMP-9; Bone morphogenetic protein; Bone morphogenetic protein 9; Gdf2; GDF-2; growth differentiation factor 2; growth/differentiation factor 2; HHT5
• Common Name: BMP9
• Gene Symbol: GDF2
• Biological Activity: Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 0.5-1.9 ng/ml
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Sequence: SAGAGSHCQK TSLRVNFEDI GWDSWIIAPKE YEAYECKGGC FFPLADDVTPTK HAIVQTLVHL KFPTKVGKAC CVPTKLSPIS VLYKDDMGVP TLKYHYEGMS VAECGCR
• Content And Storage: -20°C
• Expression System: CHO cells
• Form: Lyophilized
• Purity or Quality Grade: ≥ 95% by SDS-PAGE gel and HPLC analyses.