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Invitrogen™ Human GBA2 (aa 612-755) Control Fragment Recombinant Protein

Product Code. 30203410
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30203410

Brand: Invitrogen™ RP92883

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This item is not returnable. View return policy

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (90%), Rat (90%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-54955 (PA5-54955. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Non-lysosomal glucosylceramidase that catalyzes the conversion of glucosylceramide (GlcCer) to free glucose and ceramide. Involved in sphingomyelin generation and prevention of glycolipid accumulation. May also catalyze the hydrolysis of bile acid 3-O-glucosides, however, the relevance of such activity is unclear in vivo. Plays a role in central nevous system development. Required for proper formation of motor neuron axons.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q9HCG7
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 57704
Name Human GBA2 (aa 612-755) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias 3.2.1.45; AD035; Beta-glucocerebrosidase 2; beta-glucosidase 2; bile acid; bile acid beta-glucosidase; Bile acid beta-glucosidase GBA2; Bile acid glucosyl transferase GBA2; Cholesterol glucosyltransferase GBA2; Cholesteryl-beta-glucosidase GBA2; F630034E04; GBA2; glucosidase beta 2; glucosidase, beta (bile acid) 2; glucosylceramidase 2; glucosylceramidase beta 2; Kiaa1605; NLGase; non-lysosomal glucosylceramidase; SPG46
Common Name GBA2
Gene Symbol GBA2
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence HDTADWKDLNLKFVLQVYRDYYLTGDQNFLKDMWPVCLAVMESEMKFDKDHDGLIENGGYADQTYDGWVTTGPSAYCGGLWLAAVAVMVQMAALCGAQDIQDKFSSILSRGQEAYERLLWNGRYYNYDSSSRPQSRSVMSDQCA
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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