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Invitrogen™ Human FREM2 (aa 2326-2451) Control Fragment Recombinant Protein

Product Code. 30201407
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30201407

Brand: Invitrogen™ RP90330

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This item is not returnable. View return policy

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (86%), Rat (86%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-55986 (PA5-55986. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

FREM2 is a member of the FRAS1-related extracellular matrix protein family and like FREM1, mutations in the FREM2 gene are associated with Fraser syndrome. FREM2 localizes to the basement membrane, forming a ternary complex that plays a role in epidermal-dermal interactions during morphogenetic processes and is thought to be required for maintaining the integrity of the skin epithelium and the differentiated state of renal epithelia. The FREM2 gene is one of several genes whose transcription is affecteded by TFAP2C, a transcription factor involved in mammary development, differentiation, and oncogenesis.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q5SZK8
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 341640
Name Human FREM2 (aa 2326-2451) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias 6030440P17Rik; 8430406N05Rik; b2b1562Clo; ECM3 homolog; FRAS1 related extracellular matrix protein 2; FRAS1-related extracellular matrix protein 2; FREM2; Gm409; my; ne; NV domain containing protein NV1; NV domain-containing protein 1; Nv1
Common Name FREM2
Gene Symbol FREM2
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence TFDGVREMREAFTVHLKPDENMIAEMQLTKAIVYIEEMSSMADVTFPSVPQIVSLLMYDDTSKAKESAEPMSGYPVICITACNPKYSDYDKTGSICASENINDTLTRYRWLISAPAGPDGVTSPMR
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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