Invitrogen™ Human FRAT1 (aa 145-165) Control Fragment Recombinant Protein

Product Code. 30197223

Brand: Invitrogen™ RP105010

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (67%), Rat (67%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-84248 (PA5-84248. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

The protein encoded by this gene belongs to the GSK-3-binding protein family. The protein inhibits GSK-3-mediated phosphorylation of beta-catenin and positively regulates the Wnt signaling pathway. It may function in tumor progression and in lymphomagenesis. [provided by RefSeq, Oct 2008].

Specifications

• Accession Number: Q92837
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Blocking Assay, Control
• Formulation: 1 M urea, PBS with no preservative; pH 7.4
• Gene ID (Entrez): 10023
• Name: Human FRAT1 (aa 145-165) Control Fragment
• Quantity: 100 μL
• Regulatory Status: RUO
• Gene Alias: AW060382; Frat1; FRAT-1; frequently rearranged in advanced T cell lymphomas; frequently rearranged in advanced T-cell lymphomas 1; Proto-oncogene FRAT1
• Common Name: FRAT1
• Gene Symbol: FRAT1
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: PQADLDGPPGAGKQGIPQPLS
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining