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Gibco™ Human Flt-3 Ligand (FLT3L), Animal-Free Recombinant Protein, PeproTech®

Product Code. 17886618
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17886618 2 μg 2µg
17896438 250 μg 250µg
17876578 50 μg 50µg
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Product Code. 17886618 Supplier Gibco™ Supplier No. AF300192UG

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Description

Recombinant Protein

Recombinant Human Flt3-Ligand is a soluble 17.6 kDa protein consisting of 155 amino acid residues. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

FLT3LG (Fms Related Tyrosine Kinase 3 Ligand) is a Protein Coding gene. Diseases associated with FLT3LG include Aplastic Anemia and Brain Cancer. Among its related pathways are Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers and Ras signaling pathway. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and cytokine activity. Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8-positive classical DCs and their CD103-positive tissue counterparts.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P49771
For Use With (Application) Control, Bioactivity
Format Lyophilized
Formulation Protein with no preservative
Gene ID (Entrez) 2323
Molecular Weight (g/mol) 17.6 kDa
Name Human Flt-3 Ligand (FLT3L), Animal-Free
Purification Method Purified
Quantity 2 μg
Storage Requirements -20°C
Regulatory Status RUO
Endotoxin Concentration <0.1 EU/μg
Gene Alias FL; Flt 3 ligand; Flt3; Flt3 L; Flt3 ligand; Flt3l; Flt3lg; fms related receptor tyrosine kinase 3 ligand; fms related tyrosine kinase 3 ligand; FMS-like tyrosine kinase 3 ligand; fms-related tyrosine kinase 3; fms-related tyrosine kinase 3 ligand; H-FLT-3-L; Ly72L; M-FLT-3-L; NEWGENE_2322792; SL cytokine
Common Name FLT3LG
Gene Symbol FLT3LG
Biological Activity The ED50 as determined by the dose-dependent stimulation of the proliferation of human AML5 cells is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 10^6 units/mg
Product Type Protein
Conjugate Unconjugated
Recombinant Recombinant
Sequence TQDCSFQHSP ISSDFAVKIR ELSDYLLQDY PVTVASNLQD EELCGGLWRL VLAQRWMERL KTVAGSKMQG LLERVNTEIH FVTKCAFQPP PSCLRFVQTN ISRLLQETSE QLVALKPWIT RQNFSRCLEL QCQPDSSTLP PPWSPRPLEA TAPTA
Content And Storage -20°C
Activity The ED50 as determined by the dose-dependent stimulation of the proliferation of human AML5 cells is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 10^6 units/mg.
Expression System E. coli
Form Lyophilized
Purity or Quality Grade ≥ 98% by SDS-PAGE gel and HPLC analyses.
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