Invitrogen™ Human FKBP6 (aa 113-197) Control Fragment Recombinant Protein

Product Code. 30213181

Brand: Invitrogen™ RP103389

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (93%), Rat (93%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-63926 (PA5-63926. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

FKBP6 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP6 is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin.This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. This protein is involved in palate formation.

Specifications

• Accession Number: O75344
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Blocking Assay, Control
• Formulation: 1 M urea, PBS with no preservative; pH 7.4
• Gene ID (Entrez): 8468
• Name: Human FKBP6 (aa 113-197) Control Fragment
• Quantity: 100 μL
• Regulatory Status: RUO
• Gene Alias: 1700008G22Rik; 36 kDa FK506 binding protein; 36 kDa FK506-binding protein; 36 kDa FKBP; 36 kDa; As; AU017274; D5Ertd724e; FK506 binding protein 6; FK506 binding protein 6, 36 kDa; FK506-binding protein 6; FK506-binding protein 6 (36 kD); FKBP prolyl isomerase 6; FKBP prolyl isomerase family member 6 (inactive); Fkbp36; FKBP-36; FKBP6; FKBP-6; Immunophilin FKBP36; Inactive peptidyl-prolyl cis-trans isomerase FKBP6; Inactive PPIase FKBP6; MGC87179; peptidyl-prolyl cis-trans isomerase FKBP6; PPiase; PPIase FKBP6; rotamase
• Common Name: FKBP6
• Gene Symbol: Fkbp6
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: KPNYAYGTLGCPPLIPPNTTVLFEIELLDFLDCAESDKFCALSAEQQDQFPLQKVLKVAATEREFGNYLFRQNRFYDAKVRYKRA
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining