Gibco™ Human FGF-BP-1 Recombinant Protein, PeproTech®

Product Code. 17871503

Brand: Gibco™ 1006625UG

Description

Recombinant Protein

Recombinant Human FGF-BP-1 expressed in E.coli is a 24.0 kDa protein containing 212 amino acid residues. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

FGFBP1 encodes a secreted fibroblast growth factor carrier protein. The encoded protein plays a critical role in cell proliferation, differentiation and migration by binding to fibroblast growth factors and potentiating their biological effects on target cells. The encoded protein may also play a role in tumor growth as an angiogenic switch molecule, and expression of this gene has been associated with several types of cancer including pancreatic and colorectal adenocarcinoma. A pseudogene of this gene is also located on the short arm of chromosome 4.

Specifications

• Accession Number: Q14512
• For Use With (Application): Functional Assay
• Formulation: protein with no preservative
• Gene ID (Entrez): 9982
• Molecular Weight (g/mol): 23.9 kDa
• Name: Human FGF-BP-1
• Quantity: 25 μg
• Source: E. coli
• Regulatory Status: RUO
• Endotoxin Concentration: <1 EU/ μg
• Gene Alias: 17 kDa HBGF-binding protein; 17 kDa heparin-binding growth factor-binding protein; FGF-binding protein 1; FGFBP; FGF-BP; Fgfbp1; FGF-BP1; FGFBP-1; fibroblast growth factor binding protein 1; fibroblast growth factor-binding protein 1; growth factor binding protein-1; growth factor-binding protein 1; HBP17; heparin-binding growth factor binding protein
• Common Name: FGFBP1
• Gene Symbol: FGFBP1
• Biological Activity: Determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors. The expected ED50 for this effect is 1.5-3.0 ug/ml
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Sequence: MKKKVKNGLH SKVVSEQKDT LGNTQIKQKS RPGNKGKFVT KDQANCRWAA TEQEEGISLK VECTQLDHEF SCVFAGNPTS CLKLKDERVY WKQVARNLRS QKDICRYSKT AVKTRVCRKD FPESSLKLVS STLFGNTKPR KEKTEMSPRE HIKGKETTPS SLAVTQTMAT KAPECVEDPD MANQRKTALE FCGETWSSLC TFFLSIVQDT SC
• Content And Storage: -20°C
• Expression System: E. coli
• Form: Lyophilized
• Purity or Quality Grade: ≥ 95% by SDS-PAGE gel and HPLC analyses.