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ACROBiosystems Human FcRn / FCGRT&B2M Heterodimer Protein, His Tag
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Product Code. 16447529
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Quantity:
1 mg
50 μg
Unit Size:
1mg
50µg
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16447529 50 μg 50µg
16437529 1 mg 1mg
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Product Code. 16447529 Supplier ACROBiosystems Supplier No. FCNH52W750ug

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Description

SPR & BLI verified

FCGRT & B2M heterodimer protein (FcRn complex) consist of two subunits: p51 (equivalent to FCGRT), and p14 (equivalent to beta-2-microglobulin), and forms an MHC class I-like heterodimer. Fc fragment of IgG, receptor, transporter, alpha (FCGRT) binds to the Fc region of monomeric immunoglobulins gamma and mediates the uptake of IgG from milk. FCGRT possible role in transfer of immunoglobulin G from mother to fetus. Beta-2-microglobulin (B2M) is a component of the class I major histocompatibility complex (MHC) and involved in the presentation of peptide antigens to the immune system.

Human FCGRT&B2M Heterodimer Protein, His Tag (SPR & BLI verified), produced by co-expression of FCGRT and B2M, has a calculated MW of 32.3 kDa (FCGRT) and 11.7 kDa (B2M). Subunit FCGRT is fused with a polyhistidine tag at the C-terminus and subunit Beta-2

Specifications

Accession Number NP_001129491.1 (FCGRT) and NP_004039.1 (B2M)
Molecular Weight (g/mol) 32.3 kDa (FCGRT) and 11.7 kDa (B2M)
Quantity 50 μg
Source Human FCGRT&B2M; Heterodimer Protein, His Tag (SPR and BLI verified) (FCN-H52W7) is expressed from human 293 cells (HEK293). It contains AA Ala 24 - Ser 297 (FCGRT) and Ile 21 - Met 119 (B2M) (Accession # P55899-1 (FCGRT) and P61769-1 (B2M)).
Immunogen Ala 24 - Ser 297 (FCGRT) and Ile 21 - Met 119 (B2M)
Storage Requirements -20°C
Gene Alias FcRn,FCGRT and B2M
Common Name FcRn (FCGRT and B2M)
Conjugate Unconjugated
Species Human
Protein Tag His Tag
Buffer PBS, pH7.4
Endotoxin Level Less than 1.0 EU / μg by the LAL method.
Expression System HEK293
Form Powder
Protein Subtype MABSol™ Fc Receptors
Purity or Quality Grade >95% as determined by SDS-PAGE
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