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Invitrogen™ Human FAM65A (aa 849-965) Control Fragment Recombinant Protein

Product Code. 30206089
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Quantity:
100 μL
Unit Size:
100µL
This item is not returnable. View return policy

Product Code. 30206089

Brand: Invitrogen™ RP100912

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This item is not returnable. View return policy

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (78%), Rat (78%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-52228 (PA5-52228. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Downstream effector protein for Rho-type small GTPases that plays a role in cell polarity and directional migration (PubMed:27807006). Acts as an adapter protein, linking active Rho proteins to STK24 and STK26 kinases, and hence positively regulates Golgi reorientation in polarized cell migration upon Rho activation (PubMed:27807006). Involved in the subcellular relocation of STK26 from the Golgi to cytoplasm punctae in a Rho- and PDCD10-dependent manner upon serum stimulation (PubMed:27807006). [UniProt]
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q6ZS17
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 79567
Name Human FAM65A (aa 849-965) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias 2310066E14Rik; AI837433; Fam65a; family with sequence similarity 65 member A; family with sequence similarity 65, member A; FLJ13725; Kiaa1930; protein FAM65A; Rho family-interacting cell polarization regulator 1; RIPOR1
Common Name FAM65A
Gene Symbol RIPOR1
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence HALESFSFLNEDEDEDNDVPGDRPPSSPEAGAEDSIDSPSARPLSTGCPALDAALVRHLYHCSRLLLKLGTFGPLRCQEAWALERLLREARVLEAVCEFSRRWEIPASSAQEVVQFS
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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