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Invitrogen™ Human FABP5 (E-FABP) Recombinant Protein
Description
This product contains purified recombinant human epidermal FABP protein with an N-terminal hexahistidine tag. This product may be used as a positive control in many immunological assays.
FABP5 (fatty acid binding protein 5 (psoriasis-associated)) is a proteinthat in humans is encoded by theFABP5 gene, also known as PAFABP, EFABP, E-FABP, KFABP, PA-FABP, Epidermal-type fatty acid-binding protein, Fatty acid-binding protein 5, Psoriasis-associated fatty acid-binding protein homolog. It is a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. The PAFABP cDNA encodes a 135-amino acid protein with molecular weight 15,164. This gene encodes the fatty acid binding protein found in epidermal cells, and was first identified as being upregulated inpsoriasistissue. It is though that FABPs roles include fatty acid uptake, transport, and metabolism. Kaczocha et al. (2009) identifiedFABP5and FABP7 as cytosolic proteins that transport AEA from the plasma membrane to subcellular fatty acid amide hydrolase, where it is hydrolyzed and inactivated. FABP3 did not show this specific transport function.
Specifications
Specifications
| Accession Number | Q01469 |
| Concentration | 1.25 mg/mL |
| For Use With (Application) | Control, Western Blot |
| Formulation | 20 mM tris HCl with 50% glycerol and no preservative; pH 8 |
| Gene ID (Entrez) | 2171 |
| Name | Human FABP5 (E-FABP) |
| pH Range | 8 |
| Quantity | 100 μg |
| Source | E. coli |
| Immunogen | N/A |
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