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Gibco™ Human Epiregulin Recombinant Protein, PeproTech®

E. coli Recombinant Protein

Brand:  Gibco™ 100-04-1MG

Additional Details : Weight : 0.16500kg

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Product Code. 17830093

  • £2410.00 / 1mg
Estimated Shipment: 12-08-2024
to see stock.

Description

Description

Epiregulin is an EGF-related growth factor that binds specifically to EGFR (ErbB1) and ErbB4, but not ErbB2 or ErbB3. It is expressed mainly in the placenta and peripheral blood leukocytes, as well as in certain carcinomas of the bladder, lung, kidney and colon. Epiregulin stimulates the proliferation of keratinocytes, hepatocytes, fibroblasts and vascular smooth muscle cells. It also inhibits the growth of several tumor-derived epithelial cell lines. Human Epiregulin is initially synthesized as a glycosylated 19.0 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce a 6.0 kDa mature secreted sequence.
Specifications

Specifications

O14944
protein with no preservative
5.6
1 mg
-20°C
<1 EU/μg
Ereg
Unconjugated
MVAQVSITKC SSDMNGYCLH GQCIYLVDMS QNYCRCEVGY TGVRCEHFFL
≥ 98% by SDS-PAGE gel and HPLC analyses.
Functional Assay
2069
Human Epiregulin
E. coli
RUO
Ep; Epiregulin; EPR; ER; EREG; Proepiregulin
Human
Recombinant
Lyophilized
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