Invitrogen™ Human ELOVL1 (aa 250-277) Control Fragment Recombinant Protein

Product Code. 30197845

Brand: Invitrogen™ RP103262

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (86%), Rat (86%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-63320 (PA5-63320. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Elongation of very long chain fatty acid-like (ELOVL) proteins 1-6 are members of the ELO family of proteins, which play an important role in tissue-specific biosynthesis of very long chain fatty acids and sphingolipids. The ELOVL proteins act as catalysts in fatty acid elongation reduction and localize to the endoplasmic reticulum (ER). Elongation of very long chain fatty acids protein 1 (ELOVL1), also referred to as Ssc1, is the human homolog of the yeast ELO3 protein. It is expressed in a variety of tissues and at especially high levels in stomach, skin, intestine, kidney and lung. ELOVL1 participates in the elongation of very long chain saturated and monounsaturated fatty acids of up to 26 carbons and may be required for the development of a barrier in epithelial cells and skin. ELOVL1 is also important for the formation of Myelin in the central nervous system. Impaired ELOVL1 activity may be associated with disorders of sphingolipid metabolism.

Specifications

• Accession Number: Q9BW60
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Blocking Assay, Control
• Formulation: 1 M urea, PBS with no preservative; pH 7.4
• Gene ID (Entrez): 64834
• Name: Human ELOVL1 (aa 250-277) Control Fragment
• Quantity: 100 μL
• Regulatory Status: RUO
• Gene Alias: 3-keto acyl-CoA synthase ELOVL1; AA407424; BB151133; CGI88; CGI-88; elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1; elongation of very long chain fatty acids protein 1; ELOVL FA elongase 1; ELOVL fatty acid elongase 1; ELOVL1; sequence similarity to Cig30 1; Ssc1; Very long chain 3-ketoacyl-CoA synthase 1; very long chain 3-oxoacyl-CoA synthase 1; very-long-chain 3-oxoacyl-CoA synthase 1
• Common Name: ELOVL1
• Gene Symbol: ELOVL1
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: FWYHSYTKGKRLPRALQQNGAPGIAKVK
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining