Invitrogen™ Human eIF5A (aa 1-25) Control Fragment Recombinant Protein

Product Code. 30198601

Brand: Invitrogen™ RP103395

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (40%), Rat (40%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-63944 (PA5-63944. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. With syntenin SDCBP, functions as a regulator of TP53/p53 and TP53/p53-dependent apoptosis. Regulates also TNF-alpha-mediated apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation. Also described as a cellular cofactor of human T-cell leukemia virus type I (HTLV-1) Rex protein and of human immunodeficiency virus type 1 (HIV-1) Rev protein, essential for mRNA export of retroviral transcripts.

Specifications

• Accession Number: P63241
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Blocking Assay, Control
• Formulation: 1 M urea, PBS with no preservative; pH 7.4
• Gene ID (Entrez): 1984
• Name: Human eIF5A (aa 1-25) Control Fragment
• Quantity: 100 μL
• Regulatory Status: RUO
• Gene Alias: AA410058; D19Wsu54e; Eif4d; eIF-4 D; Eif5a; eIF-5 A; EIF5A1; eIF-5A1; eIF-5 A-1; eIF5AI; eukaryotic initiation factor 5 A; Eukaryotic initiation factor 5 A isoform 1; eukaryotic translation initiation factor 5 A; eukaryotic translation initiation factor 5 A-1; MGC104255; MGC99547; OTTHUMP00000128384; Rev-binding factor; uORF A
• Common Name: eIF5A
• Gene Symbol: EIF5A
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: MCGTGGTDSKTRRPPHRASFLKRLE
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining