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ACROBiosystems Human DR6 / TNFRSF21 Protein, Fc Tag

Product Code. 15847807
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Quantity:
1 mg
200 μg
Unit Size:
1mg
200µg
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15847807 200 μg 200µg
15837807 1 mg 1mg
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Product Code. 15847807 Supplier ACROBiosystems Supplier No. TN1H5252200UG

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Tumor necrosis factor receptor superfamily member 21 (TNFRSF21) is also known as death receptor 6 (DR6), which is a member of the TNF-receptor superfamily. TNFRSF21 contains one death domain and four TNFR-Cys repeats. TNFRSF21 / DR6 has been shown to activate NF-κB and MAPK8/JNK, and induce cell apoptosis. Through its death domain, this receptor interacts with TRADD protein, which is known to serve as an adaptor that mediates signal transduction of TNF-receptors.

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 60.2 kDa. The protein migrates as 80-95kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Specifications

Accession Number AAH17730
Molecular Weight (g/mol) 60.2 kDa
Quantity 200 μg
Source Human DR6, Fc Tag (TN1-H5252) is expressed from human 293 cells (HEK293). It contains AA Gln 42 - Leu 350 (Accession # AAH17730).
Immunogen Gln 42 - Leu 350
Storage Requirements -20°C
Gene Alias TNFRSF21,DR6,CD358,BM-018
Common Name DR6
Conjugate Unconjugated
Species Human
Protein Tag Fc Tag
Buffer 50 mM Tris, 100 mM Glycine, 150 mM NaCl, pH7.5
Endotoxin Level Less than 1.0 EU / μg by the LAL method.
Expression System HEK293
Form Powder
Protein Subtype Bio-Markers and CD Antigens
Purity or Quality Grade >90% as determined by SDS-PAGE
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