Invitrogen™ Human DLC1 (aa 355-443) Control Fragment Recombinant Protein

Product Code. 30199786

Brand: Invitrogen™ RP109847

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (79%), Rat (79%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-144899 (PA5-144899. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

This gene encodes a GTPase-activating protein that is a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. This gene functions as a tumor suppressor gene in a number of common cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene.

Specifications

• Accession Number: Q96QB1
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Blocking Assay, Control
• Formulation: 1 M urea, PBS with no preservative; pH 7.4
• Gene ID (Entrez): 10395
• Name: Human DLC1 (aa 355-443) Control Fragment
• Quantity: 100 μL
• Regulatory Status: RUO
• Gene Alias: A730069N07Rik; ARHGAP 7; ARHGAP7; deleted in liver cancer 1; deleted in liver cancer 1 protein; Deleted in liver cancer 1 protein homolog; deleted in liver cancer 1 variant 2; deleted in liver cancer variant 4; DLC 1; DLC1; Dlc-1; DLC1 Rho GTPase activating protein; DLC1 Rho GTPase activating protein; rho GTPase-activating protein 7; FLJ21120; HP; HP protein; KIAA1723; p122 RhoGAP; p122-RhoGAP; rho GTPase activating protein 7; rho GTPase-activating protein 7; RhoGAP; Rho-GTPase-activating protein 7; rho-type GTPase-activating protein 7; STARD 12; STARD12; StAR-related lipid; StAR-related lipid transfer (START) domain containing 12; stAR-related lipid transfer protein 12; START domain-containing protein 12; transfer protein 12; unm_sa1141
• Common Name: DLC1
• Gene Symbol: Dlc1
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: MVLLIMKLDQLDQDIENALSTSSSPSGTPTNLRRHVPDLESGSESGADTISVNQTRVNLSSDTESTDLPSSTPVANSGTKPKTTAIQGI
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining