Invitrogen™ Human DHX16 (aa 299-374) Control Fragment Recombinant Protein

Product Code. 30181512

Brand: Invitrogen™ RP99561

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (91%), Rat (91%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-62411 (PA5-62411. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a functional homolog of fission yeast Prp8 protein involved in cell cycle progression. This gene is mapped to the MHC region on chromosome 6p21.3, a region where many malignant, genetic and autoimmune disease genes are linked. Three transcript variants encoding different isoforms have been found for this gene.

Specifications

• Accession Number: O60231
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Blocking Assay, Control
• Formulation: 1 M urea, PBS with no preservative; pH 7.4
• Gene ID (Entrez): 8449
• Name: Human DHX16 (aa 299-374) Control Fragment
• Quantity: 100 μL
• Regulatory Status: RUO
• Gene Alias: 2410006N22Rik; ATP-dependent RNA helicase #3; DBP2; Ddx16; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 16; DEAD/H box 16; DEAH (Asp-Glu-Ala-His) box polypeptide 16; DEAH-box helicase 16; DEAH-box protein 16; Dhx16; KIAA0577; mKIAA0577; Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16; pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16; putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16; PRO2014; Prp2; PRP8; PRPF2; putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16; RNA helicase
• Common Name: DHX16
• Gene Symbol: Dhx16
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: HMPKETRGQPARAVDLVEEESGAPGEEQRRWEEARLGAASLKFGARDAASQEPKYQLVLEEEETIEFVRATQLQGD
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining