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Invitrogen™ Human DEFA4 (aa 51-97) Control Fragment Recombinant Protein

Product Code. 30206848
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30206848

Brand: Invitrogen™ RP101423

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This item is not returnable. View return policy

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (32%), Rat (32%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-62362 (PA5-62362. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes are clustered on chromosome 8. This gene differs from other genes of this family by an extra 83-base segment that is apparently the result of a recent duplication within the coding region. The protein encoded by this gene, defensin, alpha 4, is found in the neutrophils; it exhibits corticostatic activity and inhibits corticotropin stimulated corticosterone production.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P12838
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 1669
Name Human DEFA4 (aa 51-97) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias Alpha-defensin 4; corticostatin; Crp4; DEF4; Defa28; Defa4; Defcr4; defensin alpha 4; Defensin, alpha 4; defensin, alpha 4, corticostatin; defensin, alpha 4, preproprotein; defensin, alpha, 4; Defensin-related cryptdin-4; HNP-4; HP4; HP-4; Neutrophil defensin 4
Common Name DEFA4
Gene Symbol DEFA4
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence SSALQVSGSTRGMVCSCRLVFCRRTELRVGNCLIGGVSFTYCCTRVD
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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