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Invitrogen™ Human DCPS (aa 7-103) Control Fragment Recombinant Protein

Product Code. 30206769
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30206769

Brand: Invitrogen™ RP97297

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This item is not returnable. View return policy

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (85%), Rat (85%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-58865 (PA5-58865. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Necessary for the complete degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA fragments shorter than 10 nucleotides that are produced by 3'-5' exosome-mediated mRNA decay. Releases m7GMP. Can also degrade m7GDP to m7GMP. Has no activity towards mRNA molecules longer than 25 nucleotides.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q96C86
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 28960
Name Human DCPS (aa 7-103) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase; ARS; Dcps; DCS1; DCS-1; decapping enzyme, scavenger; decapping scavenger enzyme; heat shock-like protein 1; HINT5; HINT-5; Hint-related 7 meGMP-directed hydrolase; Histidine triad nucleotide-binding protein 5; histidine triad protein member 5; homolog of C. elegans 7 meGMP-directed hydrolase dcs-1; HSL1; HSPC015; m7GpppX diphosphatase; mRNA decapping enzyme; scavenger mRNA-decapping enzyme DcpS
Common Name DCPS
Gene Symbol DCPS
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence QLGKRKRELDVEEAHAASTEEKEAGVGNGTCAPVRLPFSGFRLQKVLRESARDKIIFLHGKVNEASGDGDGEDAVVILEKTPFQVEQVAQLLTGSPE
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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