Invitrogen™ Human D4 Dopamine Receptor (aa 93-112) Control Fragment Recombinant Protein

Product Code. 30198612

Brand: Invitrogen™ RP109810

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (90%), Rat (90%). This recombinant protein control fragment may be used for blocking experiments. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats.

Specifications

• Accession Number: P21917
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Blocking Assay, Control
• Formulation: 1 M urea, PBS with no preservative; pH 7.4
• Gene ID (Entrez): 1815
• Name: Human D4 Dopamine Receptor (aa 93-112) Control Fragment
• Quantity: 100 μL
• Regulatory Status: RUO
• Gene Alias: AW125663; D(2 C) dopamine receptor; D(4) dopamine receptor; D4DR; D4R; D4RA; Dopamine 4 receptor; Dopamine D4 receptor; dopamine receptor 4; dopamine receptor D4; DRD4; Drd-4; seven transmembrane helix receptor
• Common Name: D4 Dopamine Receptor
• Gene Symbol: DRD4
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: YSEVQGGAWLLSPRLCDALM
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining