Invitrogen™ Human CYP4B1 (aa 64-186) Control Fragment Recombinant Protein

Product Code. 30200479

Brand: Invitrogen™ RP101024

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (87%), Rat (87%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-82148 (PA5-82148. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. In rodents, the homologous protein has been shown to metabolize certain carcinogens; however, the specific function of the human protein has not been determined. Two transcript variants encoding slightly different isoforms have been found for this gene.

Specifications

• Accession Number: P13584
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Blocking Assay, Control
• Formulation: 1 M urea, PBS with no preservative; pH 7.4
• Gene ID (Entrez): 1580
• Name: Human CYP4B1 (aa 64-186) Control Fragment
• Quantity: 100 μL
• Regulatory Status: RUO
• Gene Alias: CYP4B1; Cyp4b-1; CYP4B1 isoform; CYP4B1-like isozyme short form; CYPIVB1; cytochrome P450 4B1; cytochrome P450 family 4 subfamily B member 1; cytochrome P450 isozyme 5; cytochrome P-450 isozyme 5; Cytochrome P450 L-2; cytochrome P450, family 4, subfamily B, polypeptide 1; cytochrome P450, subfamily 4 B, polypeptide 1; cytochrome P450, subfamily IV B, polypeptide 1; cytochrome P450, subfamily IVB, polypeptide 1; cytochrome P450-HP; microsomal monooxygenase; P450 L-2; P-450 HP; P450-isozyme 5
• Common Name: CYP4B1
• Gene Symbol: CYP4B1
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: TGSLDKVVSWAHQFPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGH
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining