Invitrogen™ Human CTHRC1 ELISA Kit

Product Code. 17194879

Brand: Invitrogen™ EH135RBX5

Description

ELISA

Human CTHRC1 quantitates human CTHRC1 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human CTHRC1.

The Collagen triple helix repeat-containing protein (CTHRC1) is a glycosylated, secreted protein that is transiently expressed in the arterial wall in response to injury where it is thought to contribute to vascular remodeling by inhibiting collagen expression and deposition and promoting cell migration. CTHRC1 is highly expressed multiple human cancers, including pancreatic cancer where it plays a significant role in the progression and metastasis of the disease by regulating migration and adhesion of tumors cells. CTHRC1 overexpression can also be used as an independent prognostic marker in gastric cancer. Mutations at this locus have been associated with Barrett esophagus and esophageal adenocarcinoma.

Specifications

• Accession Number: 1110014B07Rik; collagen triple helix repeat containing 1; collagen triple helix repeat-containing protein 1; Cthrc1; Protein NMTC1; UNQ762/PRO1550
• Assay Range: 8 to 5,000 pg/mL
• Assay Sensitivity: 8 pg/mL
• Conjugate: HRP
• Product Type: ELISA
• Sample Type: Plasma, Serum, Supernatant
• For Use With (Equipment): Colorimetric Microplate Reader
• Gene ID (Entrez): 115908
• Gene Symbol: Cthrc1
• Interassay CV: <12%
• Intraassay CV: <10
• Kit Contents: Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
• Label or Dye: HRP
• Quantity: 5 x 96 Tests
• Regulatory Status: RUO
• Sample Volume: Plasma 50 μL, Serum 50 μL, Supernatant 50 μL
• Storage Requirements: 2°C to 8°C
• Target: CTHRC1
• Test Time: 1 hrs 20 mins
• Total Assay Time: 4 hrs 45 mins