Invitrogen™ Human CROCC (aa 1031-1121) Control Fragment Recombinant Protein

Product Code. 30202515

Brand: Invitrogen™ RP93572

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (95%), Rat (95%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-54501 (PA5-54501. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Major structural component of the ciliary rootlet, a cytoskeletal-like structure in ciliated cells which originates from the basal body at the proximal end of a cilium and extends proximally toward the cell nucleus. Furthermore, is required for the correct positioning of the cilium basal body relative to the cell nucleus, to allow for ciliogenesis (PubMed:27623382). Contributes to centrosome cohesion before mitosis (PubMed:16203858). [UniProt]

Specifications

• Accession Number: Q5TZA2
• Concentration: ≥5.0 mg/mL
• For Use With (Application): Blocking Assay, Control
• Formulation: 1 M urea, PBS with no preservative; pH 7.4
• Gene ID (Entrez): 9696
• Name: Human CROCC (aa 1031-1121) Control Fragment
• Quantity: 100 μL
• Regulatory Status: RUO
• Gene Alias: ciliary rootlet coiled-coil protein; ciliary rootlet coiled-coil, rootletin; CROCC; KIAA0445; ROLT; rootletin; rootletin, ciliary rootlet protein; Tax1-binding protein 2
• Common Name: CROCC
• Gene Symbol: CROCC
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-ABP-tag
• Sequence: LEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLR
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Purity or Quality Grade: >80% by SDS-PAGE and Coomassie blue staining