Invitrogen™ Human CRIM2 Synthetic Peptide

Codice prodotto.	Quantity	Dimensione della confezione
15285359	50 μg	50µg

Codice prodotto. 15285359 Fornitore Invitrogen™ N. del fornitore PEP1453

Descrizione

Synthetic Peptide

This peptide corresponds to 15 amino acid peptide near the carboxy terminus of human CRIM2. PEP-1453 can be used as a blocking peptide with polyclonal antibody PA5-34411.

CRIM2, also known as Kielin/chordin-like protein (KCP), is a novel enhancer of BMP signaling. It binds to BMP7, a morphogen that is important for kidney development and part of the kidney's physiological response to repair of acute kidney injury, enhancing its binding to its receptor. Because of this, CRIM2 has been suggested as a potential antifibrotic therapy in acute and chronic kidney injury. CRIM2 can also interact directly with either activin or TGF-Beta1, suppressing activin- and TGF-Beta1-dependent transcription.

Specifica

• Gene ID (Entrez): 375616
• Species: Human
• Purification Method: purified
• Accession Number: Q6ZWJ8
• Common Name: CRIM2
• Concentration: 200 μg/mL
• Content And Storage: -20°C
• Description: Synthetic Peptide
• Format: Liquid
• Formulation: PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
• For Use With (Application): Blocking Assay, Control
• Gene Alias: AW060220; CRIM2; CRIM-2; cysteine rich BMP regulator 2 (chordin like); cysteine rich BMP regulator 2 (chordin-like); cysteine-rich BMP regulator 2; Cysteine-rich motor neuron 2 protein; Gm793; KCP; Kcp1; KCP-1; kielin; kielin/chordin-like protein; Kielin/chordin-like protein 1; NET67; RGD1561119
• Gene Symbol: KCP
• Lyophilized: No
• Preservative: Sodium azide
• Product Type: Peptide
• Quantity: 50 μg
• Regulatory Status: RUO
• Storage Buffer: PBS