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Invitrogen™ Human CLASP2 (aa 875-914) Control Fragment Recombinant Protein

Artikelnummer. 30209991
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Quantity:
100 μL
Pakningsstørrelse:
100µL
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Artikelnummer. 30209991

Brand: Invitrogen™ RP107542

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Beskrivelse

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-66893 (PA5-66893. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

CLASP2 is microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle.
TRUSTED_SUSTAINABILITY

Tekniske data

Accession Number O75122
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 23122
Name Human CLASP2 (aa 875-914) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias 1500004F14Rik; 8030404L10Rik; C77448; CLASP2; CLASP2alpha; CLASP2beta; CLASP2gamma; CLIP associating protein 2; CLIP-associating protein 2; CLIP-associating protein CLASP2; cytoplasmic linker associated protein 2; cytoplasmic linker-associated protein 2; hOrbit2; Kiaa0627; mKIAA0627; multiple asters (Mast)-like homolog 2; protein Orbit homolog 2
Common Name CLASP2
Gene Symbol Clasp2
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence LHNHLRNTGNGTQSSMGSPLTRPTPRSPANWSSPLTSPTN
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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