R&D Systems™ Human CL-K1/COLEC11 (NP_076932) VersaClone cDNA

Product Code. 18741479

Brand: R&D Systems™ RDC2689

Description

This shuttle vector contains the complete ORF for the gene of interest, along with a Kozak consensus sequence for optimal translation initiation. It is inserted NotI to AscI. The gene insert is flanked with convenient multiple cloning sites which can be used to easily cut and transfer the gene cassette into your desired expression vector.

• Also known as: 3MC2; CLK1; CLK1-I; CL-K1-II; CL-K1-IIa; CL-K1-IIb
• COLEC11 is a member of the collectin family of C-type lectins that possess collagen-like sequences and carbohydrate recognition domains.
• Collectins are secreted proteins that play important roles in the innate immune system by binding to carbohydrate antigens on microorganisms, facilitating their recognition and removal.
• COLEC11 binds to multiple sugars with a preference for fucose and mannose. Mutations in this gene are a cause of 3MC syndrome-2.
• Alternatively spliced transcripts encoding different proteins have been described.
• The insert is sequence verified and the entire plasmid DNA and insert translated sequences are provided.
• For reasearch use only. Not for use in humans.

Specifications

• Gene: hCOLEC11
• Accession Number: NP_076932
• Concentration: 10 μg at 0.2 μg/μL
• Formulation: cDNA is provided in 10 mM Tris-Cl, pH 8.5
• Insert Type: 829 bp
• Gene ID (Entrez): 78989
• Content And Storage: Store the unopened product at -20°C to -70°C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
• Species: Human
• Quantity: 10 μg